3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL7A1 Gene (Entity type)	-0.0071958685
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT3 Gene (Entity type)	0.008866774
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EREG Gene (Entity type)	0.010148663
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.018322704
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAG3 Gene (Entity type)	-0.008238212
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OLFM4 Gene (Entity type)	0.009189559
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Ro-28-1675 Compound (Entity type)	0.4864649176597595
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA1A Gene (Entity type)	-0.01366723
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.014164372
3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F2R Gene (Entity type)	-0.0070719

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL7A1
Gene (Entity type)
-0.0071958685

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT3
Gene (Entity type)
0.008866774

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EREG
Gene (Entity type)
0.010148663

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.018322704

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAG3
Gene (Entity type)
-0.008238212

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OLFM4
Gene (Entity type)
0.009189559

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Ro-28-1675
Compound (Entity type)
0.4864649176597595

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA1A
Gene (Entity type)
-0.01366723

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.014164372

3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
F2R
Gene (Entity type)
-0.0070719

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