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Promethazine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Promethazine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Promethazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-2B adrenergic receptor Protein (Entity type)	Ki
	Promethazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M3 Protein (Entity type)	Ki
	Promethazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Muscarinic acetylcholine receptor M5 Protein (Entity type)	Ki
	Promethazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	-0.005223164
	Promethazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TXNDC9 Gene (Entity type)	-0.0058600926
	Promethazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VEGFA Gene (Entity type)	-0.004770629
	Promethazine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Gly-Gly-PALO Compound (Entity type)	0.3407038748264313
	Promethazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.0050817854
	Promethazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TLE1 Gene (Entity type)	0.0048235976
	Promethazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PEG3 Gene (Entity type)	0.006595388

Promethazine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-2B adrenergic receptor
Protein (Entity type)
Ki

Promethazine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M3
Protein (Entity type)
Ki

Promethazine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Muscarinic acetylcholine receptor M5
Protein (Entity type)
Ki

Promethazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
-0.005223164

Promethazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TXNDC9
Gene (Entity type)
-0.0058600926

Promethazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
VEGFA
Gene (Entity type)
-0.004770629

Promethazine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Gly-Gly-PALO
Compound (Entity type)
0.3407038748264313

Promethazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINA1
Gene (Entity type)
0.0050817854

Promethazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TLE1
Gene (Entity type)
0.0048235976

Promethazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PEG3
Gene (Entity type)
0.006595388

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