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merestinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View merestinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	merestinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPM1H Gene (Entity type)	0.0064659077
	merestinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIK3R3 Gene (Entity type)	-0.0066195913
	merestinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.0055263555
	merestinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Mer Protein (Entity type)	Kd
	merestinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Efatutazone Compound (Entity type)	0.2621422708034515
	merestinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MYLK Gene (Entity type)	0.006062967
	merestinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	-0.0058540255
	merestinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NUDT9 Gene (Entity type)	-0.0054866797
	merestinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage-stimulating protein receptor Protein (Entity type)	IC50
	merestinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AIM2 Gene (Entity type)	-0.005215045

merestinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PPM1H
Gene (Entity type)
0.0064659077

merestinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIK3R3
Gene (Entity type)
-0.0066195913

merestinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.0055263555

merestinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase Mer
Protein (Entity type)
Kd

merestinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Efatutazone
Compound (Entity type)
0.2621422708034515

merestinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MYLK
Gene (Entity type)
0.006062967

merestinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
-0.0058540255

merestinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NUDT9
Gene (Entity type)
-0.0054866797

merestinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Macrophage-stimulating protein receptor
Protein (Entity type)
IC50

merestinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AIM2
Gene (Entity type)
-0.005215045

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