N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-hydroxy-7-oxo-7-(2-(4-(pyrimidin-5-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	0.4706655740737915
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EMP3 Gene (Entity type)	-0.018700449
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MTA1 Gene (Entity type)	-0.019353261
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STUB1 Gene (Entity type)	0.020405592
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PON2 Gene (Entity type)	-0.02521885
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIR Gene (Entity type)	-0.018428275
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL1A2 Gene (Entity type)	-0.018146446
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LMO3 Gene (Entity type)	-0.018367829
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A2 Gene (Entity type)	0.01854683
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Histone deacetylase 1 Protein (Entity type)	IC50

N-hydroxy-7-oxo-7-(2-(4-(pyrimidin-5-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
0.4706655740737915

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EMP3
Gene (Entity type)
-0.018700449

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MTA1
Gene (Entity type)
-0.019353261

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STUB1
Gene (Entity type)
0.020405592

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PON2
Gene (Entity type)
-0.02521885

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIR
Gene (Entity type)
-0.018428275

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL1A2
Gene (Entity type)
-0.018146446

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LMO3
Gene (Entity type)
-0.018367829

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A2
Gene (Entity type)
0.01854683

N-hydroxy-7-oxo-7-(2-(4-(thiophen-2-yl)benzylidene)hydrazinyl)heptanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Histone deacetylase 1
Protein (Entity type)
IC50

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Knowledge Graph Assertions

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