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mecamylamine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View mecamylamine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	mecamylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STC1 Gene (Entity type)	0.005468011
	mecamylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.0046316
	mecamylamine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Hypertensive disease Disease or Phenotype (Entity type)
	mecamylamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Fomepizole Compound (Entity type)	0.4020614326000213
	mecamylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BLNK Gene (Entity type)	-0.0041497843
	mecamylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STK10 Gene (Entity type)	0.0057119476
	1-[2-(2-Hydroxy-3-propylamino-propoxy)-phenyl]-3-phenyl-propan-1-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	mecamylamine Compound (Entity type)	0.2772606015205383
	mecamylamine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Neuronal acetylcholine receptor subunit alpha-3 Protein (Entity type)	IC50
	mecamylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI27 Gene (Entity type)	-0.006081515
	mecamylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GEM Gene (Entity type)	-0.0041877674

mecamylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STC1
Gene (Entity type)
0.005468011

mecamylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.0046316

mecamylamine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Hypertensive disease
Disease or Phenotype (Entity type)

mecamylamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Fomepizole
Compound (Entity type)
0.4020614326000213

mecamylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BLNK
Gene (Entity type)
-0.0041497843

mecamylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STK10
Gene (Entity type)
0.0057119476

1-[2-(2-Hydroxy-3-propylamino-propoxy)-phenyl]-3-phenyl-propan-1-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
mecamylamine
Compound (Entity type)
0.2772606015205383

mecamylamine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Neuronal acetylcholine receptor subunit alpha-3
Protein (Entity type)
IC50

mecamylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI27
Gene (Entity type)
-0.006081515

mecamylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GEM
Gene (Entity type)
-0.0041877674

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