4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	0.040902235
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOSB Gene (Entity type)	0.025879614
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DPYSL2 Gene (Entity type)	-0.021428168
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCL20 Gene (Entity type)	0.021204349
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PPP1R15A Gene (Entity type)	0.023702983
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RRS1 Gene (Entity type)	-0.021756155
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	cinobufagin Compound (Entity type)	0.8275578618049622
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL2 Gene (Entity type)	0.021317104
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB2 Gene (Entity type)	0.028049111
4-((3S,5R,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium-transporting ATPase alpha chain 2 Protein (Entity type)	IC50