5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	-0.0148886675
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AARS1 Gene (Entity type)	-0.009638683
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	-0.013265542
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	-0.014176073
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.708084762096405
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBP1 Gene (Entity type)	0.008801636
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KLHDC2 Gene (Entity type)	0.009129381
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMC1A Gene (Entity type)	0.008965474
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	0.7265859842300415
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PNMA2 Gene (Entity type)	0.009222984

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
-0.0148886675

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AARS1
Gene (Entity type)
-0.009638683

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
-0.013265542

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
-0.014176073

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.708084762096405

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBP1
Gene (Entity type)
0.008801636

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KLHDC2
Gene (Entity type)
0.009129381

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMC1A
Gene (Entity type)
0.008965474

1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
0.7265859842300415

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PNMA2
Gene (Entity type)
0.009222984

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