2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	-0.017186273
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFD Gene (Entity type)	0.009202074
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PODXL Gene (Entity type)	0.008793614
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Bromhexine Compound (Entity type)	0.2699111998081207
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FRZB Gene (Entity type)	0.008953739
(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	0.1959148943424224
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.008910358
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SULT1C2 Gene (Entity type)	-0.009038676
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC27A2 Gene (Entity type)	-0.009847887
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPA2 Gene (Entity type)	0.011838136

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
-0.017186273

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFD
Gene (Entity type)
0.009202074

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PODXL
Gene (Entity type)
0.008793614

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Bromhexine
Compound (Entity type)
0.2699111998081207

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FRZB
Gene (Entity type)
0.008953739

(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
0.1959148943424224

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.008910358

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SULT1C2
Gene (Entity type)
-0.009038676

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC27A2
Gene (Entity type)
-0.009847887

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (corynanthine)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPA2
Gene (Entity type)
0.011838136

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