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istradefylline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View istradefylline's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LUM Gene (Entity type)	0.005565205
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RND3 Gene (Entity type)	0.005744059
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	POSTN Gene (Entity type)	0.005835371
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AEBP1 Gene (Entity type)	0.005287195
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EDN1 Gene (Entity type)	0.005931289
	istradefylline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Adenosine receptor A2b Protein (Entity type)	Ki
	istradefylline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.005152328
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COL1A2 Gene (Entity type)	0.0062211943
	istradefylline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDLIM1 Gene (Entity type)	0.0054979865
	istradefylline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN8 Gene (Entity type)	-0.004715983

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LUM
Gene (Entity type)
0.005565205

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RND3
Gene (Entity type)
0.005744059

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
POSTN
Gene (Entity type)
0.005835371

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AEBP1
Gene (Entity type)
0.005287195

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EDN1
Gene (Entity type)
0.005931289

istradefylline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Adenosine receptor A2b
Protein (Entity type)
Ki

istradefylline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.005152328

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COL1A2
Gene (Entity type)
0.0062211943

istradefylline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDLIM1
Gene (Entity type)
0.0054979865

istradefylline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN8
Gene (Entity type)
-0.004715983

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