5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fer Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase kinase kinase 9 Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK2 Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	High affinity nerve growth factor receptor Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Focal adhesion kinase 1 Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	ALK tyrosine kinase receptor Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein-tyrosine kinase 2-beta Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase Fes/Fps Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Activated CDC42 kinase 1 Protein (Entity type)	IC50
5-(6-Amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)-phenyl]ethoxy}pyridin-3-yl)-2-[(2R)-1,2-dihydroxypropan-2-yl]-1,3-thiazole-4-carbonitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	NT-3 growth factor receptor Protein (Entity type)	IC50