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MK-5108 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MK-5108's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	MK-5108 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK2 Protein (Entity type)	Kd
	MK-5108 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Breakpoint cluster region protein Protein (Entity type)	Kd
	MK-5108 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Mebendazole Compound (Entity type)	0.4762623012065887
	MK-5108 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT2A Gene (Entity type)	0.0058091623
	MK-5108 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPM Gene (Entity type)	0.006299744
	MK-5108 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	0.005583499
	MK-5108 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.0065149786
	MK-5108 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BEX4 Gene (Entity type)	-0.0061194105
	MK-5108 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.006716014
	MK-5108 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMSB15A Gene (Entity type)	-0.005422718

MK-5108
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK2
Protein (Entity type)
Kd

MK-5108
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Breakpoint cluster region protein
Protein (Entity type)
Kd

MK-5108
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Mebendazole
Compound (Entity type)
0.4762623012065887

MK-5108
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT2A
Gene (Entity type)
0.0058091623

MK-5108
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPM
Gene (Entity type)
0.006299744

MK-5108
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BUB1
Gene (Entity type)
0.005583499

MK-5108
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PERP
Gene (Entity type)
-0.0065149786

MK-5108
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BEX4
Gene (Entity type)
-0.0061194105

MK-5108
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.006716014

MK-5108
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMSB15A
Gene (Entity type)
-0.005422718

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