4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.0042071054
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC39A4 Gene (Entity type)	0.0041077286
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein tyrosine phosphatase type IVA 1 Protein (Entity type)	IC50
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Multidrug and toxin extrusion protein 1 Protein (Entity type)	IC50
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOPX Gene (Entity type)	-0.0055742236
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide Compound (Entity type)	0.3916882872581482
vardenafil Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	0.33463916182518
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AZGP1 Gene (Entity type)	-0.0063437577
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein tyrosine phosphatase type IVA 2 Protein (Entity type)	IC50
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	African Trypanosomiasis Disease or Phenotype (Entity type)

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
0.0042071054

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC39A4
Gene (Entity type)
0.0041077286

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein tyrosine phosphatase type IVA 1
Protein (Entity type)
IC50

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Multidrug and toxin extrusion protein 1
Protein (Entity type)
IC50

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOPX
Gene (Entity type)
-0.0055742236

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Compound (Entity type)
0.3916882872581482

vardenafil
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
0.33463916182518

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AZGP1
Gene (Entity type)
-0.0063437577

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein tyrosine phosphatase type IVA 2
Protein (Entity type)
IC50

4-[(5-{4-[(E)-amino(imino)methyl]phenoxy}pentyl)oxy]benzenecarboximidamide
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
African Trypanosomiasis
Disease or Phenotype (Entity type)

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Knowledge Graph Assertions

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