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Mibefradil (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Mibefradil's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Mibefradil Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 3A4 Protein (Entity type)	Ki
	Mibefradil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DNAJA3 Gene (Entity type)	-0.0056927633
	Mibefradil Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Voltage-dependent T-type calcium channel subunit alpha-1H Protein (Entity type)	IC50
	Mibefradil Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium channel protein type 9 subunit alpha Protein (Entity type)	IC50
	Mibefradil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	-0.005441749
	Mibefradil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PAN2 Gene (Entity type)	0.005313047
	Mibefradil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	0.006273549
	Mibefradil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SDC2 Gene (Entity type)	-0.0040228795
	Mibefradil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AZGP1 Gene (Entity type)	0.007372738
	Mibefradil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC26A2 Gene (Entity type)	-0.005117747

Mibefradil
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 3A4
Protein (Entity type)
Ki

Mibefradil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DNAJA3
Gene (Entity type)
-0.0056927633

Mibefradil
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Voltage-dependent T-type calcium channel subunit alpha-1H
Protein (Entity type)
IC50

Mibefradil
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium channel protein type 9 subunit alpha
Protein (Entity type)
IC50

Mibefradil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
-0.005441749

Mibefradil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PAN2
Gene (Entity type)
0.005313047

Mibefradil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
0.006273549

Mibefradil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SDC2
Gene (Entity type)
-0.0040228795

Mibefradil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AZGP1
Gene (Entity type)
0.007372738

Mibefradil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC26A2
Gene (Entity type)
-0.005117747

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