2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMG20B Gene (Entity type)	-0.010935296
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SEMA3C Gene (Entity type)	-0.009818729
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Met-leu-phe Compound (Entity type)	0.2994199097156524
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHRS2 Gene (Entity type)	-0.00966043
2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4,4-dimethyl-4H-isoquinoline-1,3-dione Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	0.3084084987640381
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Neuronal acetylcholine receptor subunit alpha-7 Protein (Entity type)	Kd
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	GW9508 Compound (Entity type)	0.3069745898246765
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RBP1 Gene (Entity type)	0.009991062
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DEFB1 Gene (Entity type)	0.009711261
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADM Gene (Entity type)	-0.009474337

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMG20B
Gene (Entity type)
-0.010935296

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SEMA3C
Gene (Entity type)
-0.009818729

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Met-leu-phe
Compound (Entity type)
0.2994199097156524

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHRS2
Gene (Entity type)
-0.00966043

2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4,4-dimethyl-4H-isoquinoline-1,3-dione
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
0.3084084987640381

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Neuronal acetylcholine receptor subunit alpha-7
Protein (Entity type)
Kd

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
GW9508
Compound (Entity type)
0.3069745898246765

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RBP1
Gene (Entity type)
0.009991062

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DEFB1
Gene (Entity type)
0.009711261

2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADM
Gene (Entity type)
-0.009474337

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