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Canagliflozin (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Canagliflozin's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Canagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB1 Gene (Entity type)	0.003288103
	Canagliflozin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium/glucose cotransporter 2 Protein (Entity type)	IC50
	Canagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLPI Gene (Entity type)	0.0030475939
	Canagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKSL1 Gene (Entity type)	0.0028785253
	Canagliflozin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DEGS1 Gene (Entity type)	-0.0033747766
	Canagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB5 Gene (Entity type)	0.0026662985
	Canagliflozin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEP15 Gene (Entity type)	-0.0027676956
	Canagliflozin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	-0.005044002
	Canagliflozin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INHBA Gene (Entity type)	-0.0041387016
	Canagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100P Gene (Entity type)	0.0038223125

Canagliflozin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINB1
Gene (Entity type)
0.003288103

Canagliflozin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium/glucose cotransporter 2
Protein (Entity type)
IC50

Canagliflozin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLPI
Gene (Entity type)
0.0030475939

Canagliflozin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKSL1
Gene (Entity type)
0.0028785253

Canagliflozin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DEGS1
Gene (Entity type)
-0.0033747766

Canagliflozin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINB5
Gene (Entity type)
0.0026662985

Canagliflozin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CEP15
Gene (Entity type)
-0.0027676956

Canagliflozin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KDM5D
Gene (Entity type)
-0.005044002

Canagliflozin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INHBA
Gene (Entity type)
-0.0041387016

Canagliflozin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100P
Gene (Entity type)
0.0038223125

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