(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	BMP-2-inducible protein kinase Protein (Entity type)	Kd
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK3 Protein (Entity type)	IC50
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase kinase kinase 19 Protein (Entity type)	Kd
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK1 Protein (Entity type)	IC50
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Tyrosine-protein kinase JAK2 Protein (Entity type)	IC50
(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Non-receptor tyrosine-protein kinase TYK2 Protein (Entity type)	IC50

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
BMP-2-inducible protein kinase
Protein (Entity type)
Kd

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK3
Protein (Entity type)
IC50

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase kinase kinase 19
Protein (Entity type)
Kd

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK1
Protein (Entity type)
IC50

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Tyrosine-protein kinase JAK2
Protein (Entity type)
IC50

(R)-3-(3-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]-pyrrolo[2,3-h][1,6]naphthyridin-4-yl)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Non-receptor tyrosine-protein kinase TYK2
Protein (Entity type)
IC50

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