4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Hypoxanthine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	0.4099868535995483
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.01533671
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EFNA1 Gene (Entity type)	-0.00874165
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	0.0112110255
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMDHD2 Gene (Entity type)	0.011525593
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LAPTM4B Gene (Entity type)	-0.0123805
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.013325974
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM3A Gene (Entity type)	0.01058093
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	0.011448279
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTER Gene (Entity type)	-0.008369387

Hypoxanthine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
0.4099868535995483

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.01533671

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EFNA1
Gene (Entity type)
-0.00874165

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
0.0112110255

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMDHD2
Gene (Entity type)
0.011525593

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LAPTM4B
Gene (Entity type)
-0.0123805

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RRM2
Gene (Entity type)
0.013325974

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM3A
Gene (Entity type)
0.01058093

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A3
Gene (Entity type)
0.011448279

4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PTER
Gene (Entity type)
-0.008369387

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