N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KEAP1 Gene (Entity type)	-0.018186761
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SORBS3 Gene (Entity type)	-0.018920425
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PXMP2 Gene (Entity type)	0.0160573
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNA11 Gene (Entity type)	0.019080954
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP1B1 Gene (Entity type)	-0.023025319
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADH1B Gene (Entity type)	-0.019258667
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SFRP1 Gene (Entity type)	-0.015925338
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Histone deacetylase 2 Protein (Entity type)	IC50
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RNF167 Gene (Entity type)	0.016200766
N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	0.015297167

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KEAP1
Gene (Entity type)
-0.018186761

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SORBS3
Gene (Entity type)
-0.018920425

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PXMP2
Gene (Entity type)
0.0160573

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GNA11
Gene (Entity type)
0.019080954

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYP1B1
Gene (Entity type)
-0.023025319

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADH1B
Gene (Entity type)
-0.019258667

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SFRP1
Gene (Entity type)
-0.015925338

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Histone deacetylase 2
Protein (Entity type)
IC50

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RNF167
Gene (Entity type)
0.016200766

N-hydroxy-7-(2-((2'-methylbiphenyl-4-yl)methylene)hydrazinyl)-7-oxoheptanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
0.015297167

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Knowledge Graph Assertions

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