(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRYBG1 Gene (Entity type)	0.004111255
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FBXO11 Gene (Entity type)	-0.0044936915
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAGEA12 Gene (Entity type)	0.003653131
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBA1 Gene (Entity type)	0.004044817
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CSGALNACT1 Gene (Entity type)	0.004611424
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASPN Gene (Entity type)	-0.0061081154
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	pirenoxine Compound (Entity type)	0.3409723341464996
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1B10 Gene (Entity type)	-0.004810734
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	pregnenolone Compound (Entity type)	0.3084639012813568
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Transient receptor potential cation channel subfamily V member 1 Protein (Entity type)	IC50

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRYBG1
Gene (Entity type)
0.004111255

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FBXO11
Gene (Entity type)
-0.0044936915

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAGEA12
Gene (Entity type)
0.003653131

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBA1
Gene (Entity type)
0.004044817

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CSGALNACT1
Gene (Entity type)
0.004611424

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASPN
Gene (Entity type)
-0.0061081154

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
pirenoxine
Compound (Entity type)
0.3409723341464996

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1B10
Gene (Entity type)
-0.004810734

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
pregnenolone
Compound (Entity type)
0.3084639012813568

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Transient receptor potential cation channel subfamily V member 1
Protein (Entity type)
IC50

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