2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.00332031
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD40 Gene (Entity type)	0.0038121266
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BRD4 Gene (Entity type)	-0.0030046897
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP7 Gene (Entity type)	0.0035094132
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BCAT1 Gene (Entity type)	0.0033417402
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	XIST Gene (Entity type)	0.0034664918
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Travoprost Compound (Entity type)	0.3746183514595032
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TUBB2A Gene (Entity type)	-0.0036783332
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AGT Gene (Entity type)	0.0037321215
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.0041144635

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PIEZO1
Gene (Entity type)
-0.00332031

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD40
Gene (Entity type)
0.0038121266

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BRD4
Gene (Entity type)
-0.0030046897

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FABP7
Gene (Entity type)
0.0035094132

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BCAT1
Gene (Entity type)
0.0033417402

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
XIST
Gene (Entity type)
0.0034664918

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Travoprost
Compound (Entity type)
0.3746183514595032

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TUBB2A
Gene (Entity type)
-0.0036783332

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AGT
Gene (Entity type)
0.0037321215

2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
0.0041144635

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