PR002085 (Project)

Id Namespace:

UCSD Metabolomics Workbench

Identifier Namespace (Entity type)

Dcc Asset:

MW submission packet 20250922.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M83R6P

Description:The goal of the project is to determine the role of sphingolipid metabolism in atherosclerosis induced by dietary trans fat. We analyzed lipid metabolites in Huh7 cells following various fatty acid treatments, with specific focus on cis and trans unsaturated fatty acids. Additionally, we analyzed lipid metabolites in plasma and liver of Ldlr-/- mice fed high-fat diets enriched in cis or trans fatty acids in the presence or absence of myriocin, a pharmacological inhibitor of Serine palmitoyltransferase (SPT), the initial rate-limiting enzyme of sphingolipid biosynthesis.

Results found

Linked to

	Label	Description
	PPR00001 Project (Entity type)	Metabolomics
	SU003504 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003505 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003500 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003514 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003515 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003472 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003479 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003502 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project
	SU003481 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002085 project

PPR00001

Project (Entity type)

Metabolomics

SU003504

Subject (Entity type)