Description:In this study, we conducted lipidomic analyses of NTM-PD using lung tissues and serum. First, we aimed to identify characteristic lipid profiles associated with diverse geospatial lesions, enabling correlations with specific pathological findings. Next, we examined how these lesion-specific lipidomic profiles are reflected in serum relative to disease severity. Through these analyses, we sought to deepen our understanding of the role of lipid profiles in the pathophysiology of NTM-PD.