PR000783 (Project)

Id Namespace:

UCSD Metabolomics Workbench

Identifier Namespace (Entity type)

Dcc Asset:

MW submission packet 20250922.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8G970

Description:Particulate matter (PM) exposure and metabolic syndrome (MetSyn) coexist in both industrialized and developing nations. PM and MetSyn are strong risk factors for chronic obstructive pulmonary disease (COPD) and asthma. After the World Trade Center collapse in 9/11/2001, PM-exposed individuals from the Fire Department of New York City (FDNY) developed a progressively lung disease. This nested case-cohort study is composed of never smoking, WTC exposed firefighters with normal pre-9/11 lung function presenting for subspecialty pulmonary evaluation (SPE) before March 2008. Representative cohort controls with serum drawn within six months of 9/11 (n=100). FEV1 at subspecialty exam defined cases: susceptible World Trade Center Lung Injury (WTC-LI) cases (n=50) had FEV1< lower limit of normal (LLN) and resistant WTC-LI cases with FEV1 =107% predicted (n=50). This study will determine the metabolomics profile that differentiates firefighters with WTC-LI, firefighters resistant to WTC-LI, and similarly exposed cohort controls.

Results found

Linked to

	Label	Description
	PPR00001 Project (Entity type)	Metabolomics
	SU001236 Subject (Entity type)	A subject from Metabolomics produced as part of the PR000783 project
	SA081152 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA081124 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA081148 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA081127 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA081014 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA080998 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA081058 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project
	SA080974 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR000783 project