Description:This study aimed to determine metabolic patterns in cord blood associated with the development of pulmonary hypertension (PH) in human preterm infants. Umbilical cord blood was acquired from a nested case-control study of 20 premature (gestational age <37 weeks) infants with PH (cases) and 20 infants without PH (controls) selected from Prentice NICU birth cohort. Case and control infants were matched by race/ethnicity, gender, and gestational age. Archived cord blood plasma underwent metabolomics analysis.