PR002240 (Project)

Id Namespace:

UCSD Metabolomics Workbench

Identifier Namespace (Entity type)

Dcc Asset:

MW submission packet 20250922.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8325D

Description:Regulatory T cells (Tregs) are characterized by stable FOXP3 expression and controlling immune response by suppressive activity. Unique metabolic properties of Tregs are shown such as reduced glycolysis and increased oxidative phosphorylation. We have combined transcriptomics, metabolomics and lipidomics to dissect metabolic dynamics of Tregs upon activation. Combined metabolomic and lipidomic analysis showed that freshly isolated Tregs have unique metabolomic property, on the other hand, activated Tregs have unique lipidomic property. Interestingly, activated Tregs contained omega-3 polyunsaturated fatty acids (PUFA) enriched diglycerides and triglycerides.

Results found

Linked to

	Label	Description
	PPR00001 Project (Entity type)	Metabolomics
	SU003757 Subject (Entity type)	A subject from Metabolomics produced as part of the PR002240 project
	SA393431 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393436 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393438 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393434 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393430 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393433 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393441 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project
	SA393440 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002240 project

PPR00001

Project (Entity type)

Metabolomics

SU003757

Subject (Entity type)

A subject from Metabolomics produced as part of the PR002240 project

SA393431

Biosample (Entity type)