GSE213588 trametinib NF1 8 v 12 human up (Gene Set)

Dcc Asset:

rummageo chemical perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE213588_trametinib_NF1_8_v_12_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE213588_trametinib_NF1_8_v_12_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE213588_trametinib_NF1_8_v_12_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE213588_trametinib_NF1_8_v_12_human_up.

Results found

Linked to

	Label	Description
	ATF3 Gene (Entity type)	activating transcription factor 3
	CYP1B1 Gene (Entity type)	cytochrome P450 family 1 subfamily B member 1
	TM4SF1 Gene (Entity type)	transmembrane 4 L six family member 1
	HSPA1A Gene (Entity type)	heat shock protein family A (Hsp70) member 1A
	SERPINE2 Gene (Entity type)	serpin family E member 2
	PHLDA1 Gene (Entity type)	pleckstrin homology like domain family A member 1
	SERPINB2 Gene (Entity type)	serpin family B member 2
	GPRC5A Gene (Entity type)	G protein-coupled receptor class C group 5 member A
	IRS2 Gene (Entity type)	insulin receptor substrate 2
	S100A2 Gene (Entity type)	S100 calcium binding protein A2

ATF3

Gene (Entity type)

activating transcription factor 3

CYP1B1

Gene (Entity type)

cytochrome P450 family 1 subfamily B member 1

TM4SF1

Gene (Entity type)

transmembrane 4 L six family member 1

HSPA1A

Gene (Entity type)

heat shock protein family A (Hsp70) member 1A

SERPINE2

Gene (Entity type)

serpin family E member 2

PHLDA1

Gene (Entity type)

pleckstrin homology like domain family A member 1

SERPINB2

Gene (Entity type)

serpin family B member 2

GPRC5A

Gene (Entity type)

G protein-coupled receptor class C group 5 member A

IRS2

Gene (Entity type)

insulin receptor substrate 2

S100A2

Gene (Entity type)

S100 calcium binding protein A2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.