PHLDA2 (Gene)

Description: pleckstrin homology like domain family A member 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PHLDA2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PHLDA2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PHLDA2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PHLDA2.

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Gene Sets (2044)

LINCS L1000 Chem Pert Consensus Sigs (1105)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (933)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Ulixertinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.005083282
AS-605240 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.0055546034
deoxycorticosterone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.00404761
N4-(3-Bromo-phenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.013329366
SA-90377 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	0.008340088
PP-110 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.017940782
Y27632 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.0028237437
Nilotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	0.0026428415
imatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	0.0048222863
(S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	-0.0037368054