DHCR7 (Gene)

Description: 7-dehydrocholesterol reductase

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DHCR7's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DHCR7.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DHCR7.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DHCR7.

Submit

Gene Sets (1556)

LINCS L1000 Chem Pert Consensus Sigs (1020)

A gene set library provided by LINCS

KOMP2 Mouse Phenotypes 2022 (12)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (518)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
NTNCB Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.023458362
Akt inhibitor X Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.0069886553
linsitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.0031015675
Clomiphene Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.004703908
4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)-2-methoxybenzoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.005202086
Tariquidar Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.007970354
amitriptyline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.009046053
SA-419083 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.006861816
4-hydroxytamoxifen Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	0.0076457784
DHCR7 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	NADP Metabolite (Entity type)