MET (Gene)

Description: MET proto-oncogene, receptor tyrosine kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MET's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MET.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MET.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MET.

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Gene Sets (2770)

LINCS L1000 Chem Pert Consensus Sigs (1304)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (10)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (20)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1408)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (4)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (19)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	0.011813464
3-(1-(3-(1H-imidazol-1-yl)propyl)-1H-indol-3-yl)-4-(phenylamino)-1H-pyrrole-2,5-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.010946985
(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	0.008632755
PGE<sub>1</sub> Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.0073920274
orciprenaline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.004474788
L-755507 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.009446757
SID103905429 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	0.004549276
tacrolimus Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.002531966
VU-0418000-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.015183347
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.0027518002