HMGB2 (Gene)

Description: high mobility group box 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HMGB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HMGB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HMGB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HMGB2.

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Gene Sets (1684)

LINCS L1000 Chem Pert Consensus Sigs (811)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (869)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11113667 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0072314315
VU-0415556-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	-0.012785378
docosatrienoic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0091676125
Necrostatin-1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0042584427
N-(2-methyl-5-(2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0074896975
Lisuride Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.007876591
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0050118635
ethyl 6-(4-(benzylsulfonylcarbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.016645798
Procarbazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.003329307
SID11113337 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0042170547