CYP4B1 (Gene)

Description: cytochrome P450 family 4 subfamily B member 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYP4B1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYP4B1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYP4B1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYP4B1.

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Gene Sets (3438)

LINCS L1000 Chem Pert Consensus Sigs (1713)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (15)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1678)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (16)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (6)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11113346 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.0045133648
Zibotentan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.004518305
3-allyl-6-chloro-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.019542927
SKF-81297 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.009412856
SR59230A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.011997776
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [3-(2-dimethylamino-ethoxy)-4-methoxy-phenyl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.007361187
VU-0447126-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.019105297
N-hydroxy-7-(2-(4-hydroxy-2,6-dimethoxybenzylidene)hydrazinyl)-7-oxoheptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	-0.018815583
ZD-7155 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.007952791
LY262691 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP4B1 Gene (Entity type)	0.01371595