MMP12 (Gene)

Description: matrix metallopeptidase 12

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MMP12's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MMP12.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MMP12.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MMP12.

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Gene Sets (3135)

LINCS L1000 Chem Pert Consensus Sigs (1577)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1521)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (23)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (9)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
aminohippuric-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	-0.018401269
AT1-SHH-29 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.003537134
Felbinac Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	-0.0047771153
mirtazapine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.0043105055
WT-171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	-0.01391203
SID11114180 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	-0.0050346456
SID103905167 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.007974727
ARG-CSC-81 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.0093742665
Doxapram Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.0039266413
bis-tyrphostin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.011742814