SPP1 (Gene)

Description: secreted phosphoprotein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SPP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SPP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SPP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SPP1.

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Gene Sets (1987)

LINCS L1000 Chem Pert Consensus Sigs (1514)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (10)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (9)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (424)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (19)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (7)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Flavoxate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.007695192
N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.003397035
PD-123319 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.0049432856
Darapladib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.0065562874
Dimebolin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.004599426
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.0033478276
SID11113346 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.005317159
KIN001-043 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.008394865
Gaboxadol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.0123750875
Niacin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.0040242053