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CFDE Workbench

GSTA1 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:2938, GST-epsilon, GST2, GSTA1, GSTA1-1, GTH1, HGNC:4626, MIM:138359, NM_001319059, NM_145740, NP_001305988, NP_665683, XM_005249034, XP_005249091, glutathione S-transferase alpha 1
Omim:OMIM:138359
Id:ENSG00000243955
Hgnc:HGNC:4626
Entrez:2938
Ensembl:ENSG00000243955
Description:glutathione S-transferase alpha 1
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GSTA1's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GSTA1.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GSTA1.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GSTA1.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSTA1.

Results found

Linked to

 

Label

Description

 

Gene Set

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

T61-Colon Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

GSE193993 SSTR2 knockout 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE206931 WDR5 inhibition WIN 8 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE142210 2 V 5 PANOBINOSTAT HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125014 enzalutamide prostate gland 6 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE180321 imperatorin 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125862 2 V 0 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE236502 paclitaxel 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    T60-Adrenal Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    T61-Colon Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    GSE193993 SSTR2 knockout 4 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE206931 WDR5 inhibition WIN 8 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE142210 2 V 5 PANOBINOSTAT HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125014 enzalutamide prostate gland 6 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE180321 imperatorin 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125862 2 V 0 DEXAMETHASONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE236502 paclitaxel 2 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.