HLA-DPA1 (Gene)

Entrez Gene ID: 3113

Description: major histocompatibility complex, class II, DP alpha 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DPA1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-DPA1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DPA1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DPA1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DPA1.

Gene Sets (1906)

LINCS L1000 Chem Pert Consensus Sigs (459)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (322)

A gene set library provided by LINCS

rummageo gene perturbations (165)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (229)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (537)

A gene set library provided by LINCS

rummageo chemical perturbations (181)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

HuBMAP ASCT-B (2)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

Source	Relation	Target	Evidence
VU-0403126 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	-0.008785846
Fenoldopam Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.003191567
(3-amino-1-hydroxy-1-phosphono-propyl)-phosphonic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.0046179807
KFGENEBIN:HLA-DPA1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)
Treprostinil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	-0.010055754
SA-1463814 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.008566227
Tozadenant Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.0046061897
E-7449 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.020938752
Liver_L2_CD1c-positive myeloid dendritic cell Anatomy (Entity type)	Has marker gene in liver Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)
abacavir Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DPA1 Gene (Entity type)	0.0034972557

VU-0403126
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
-0.008785846

Fenoldopam
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.003191567

(3-amino-1-hydroxy-1-phosphono-propyl)-phosphonic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.0046179807

KFGENEBIN:HLA-DPA1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)

Treprostinil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
-0.010055754

SA-1463814
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.008566227

Tozadenant
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.0046061897

E-7449
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.020938752

Liver_L2_CD1c-positive myeloid dendritic cell
Anatomy (Entity type)
Has marker gene in liver
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)

abacavir
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DPA1
Gene (Entity type)
0.0034972557

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.