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LGR4 (Gene)

Ensembl Gene ID: ENSG00000205213

Entrez Gene ID: 55366

Description: leucine rich repeat containing G protein-coupled receptor 4

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LGR4's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LGR4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LGR4.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LGR4.

Gene Sets (2705)

LINCS L1000 Chem Pert Consensus Sigs (624)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (695)

A gene set library provided by LINCS

rummageo gene perturbations (293)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (711)

A gene set library provided by LINCS

rummageo chemical perturbations (377)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Human BioMolecular Atlas Program

HuBMAP ASCT-B (1)

A gene set library provided by HuBMAP

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Urapidil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.0035580015
	asymmetrical-dimethylarginine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.00458145
	Lynestrenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.021167314
	proxyfan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.0076836026
	Darapladib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.005878542
	5-Azacitidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.0065784766
	hydroxytyrosol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.017002355
	Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.004257885
	UCL-2077 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	-0.009351801
	Acamprosate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGR4 Gene (Entity type)	0.00941519

Urapidil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
-0.0035580015

asymmetrical-dimethylarginine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.00458145

Lynestrenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.021167314

proxyfan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.0076836026

Darapladib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.005878542

5-Azacitidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
-0.0065784766

hydroxytyrosol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
-0.017002355

Pimavanserin; Nuplazid, 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.004257885

UCL-2077
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
-0.009351801

Acamprosate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGR4
Gene (Entity type)
0.00941519

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.