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CFDE Workbench

MICB (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:4277, HGNC:7091, MHC class I polypeptide-related sequence B, MICB, MIM:602436, NM_001289160, NM_001289161, NM_005931, NP_001276089, NP_001276090, NP_005922, PERB11.2
Omim:OMIM:602436
Id:ENSG00000204516
Hgnc:HGNC:7091
Entrez:4277
Ensembl:ENSG00000204516
Description:MHC class I polypeptide-related sequence B
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MICB's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MICB.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MICB.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MICB.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MICB.

Results found

Linked to

 

Label

Description

 

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GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

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GSE151412 sorafenib 2 v 1 human up

Gene Set (Entity type)

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Gene Set (Entity type)

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GSE115384 CELSR2 knockdown 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE99875 everolimus 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE176008 pyridoxine 4 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE120612 7 V 2 ETOPOSIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE179112 GSE179113 hydroxyl Hutt45 4 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120612 etoposide leukocyte 7 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE163297 doxorubicin 0 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE151412 sorafenib 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE142588 cinobufagin 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE115384 CELSR2 knockdown 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE99875 everolimus 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE176008 pyridoxine 4 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120612 7 V 2 ETOPOSIDE HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
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    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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