HLA-DQA1 (Gene)

Ensembl Gene ID: ENSG00000196735

Entrez Gene ID: 3117

Description: major histocompatibility complex, class II, DQ alpha 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DQA1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HLA-DQA1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DQA1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DQA1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DQA1.

Gene Sets (2915)

LINCS L1000 Chem Pert Consensus Sigs (1639)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1249)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (9)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ST-4039884 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.009530269
3-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	0.0025525296
norcitalopram Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	0.015523461
Pentolinium Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.023505596
rhodomyrtoxin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.015554273
4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.0062881475
Pemoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.009755737
2-Methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene (Olanzapine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.0055798762
SA-1463785 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	0.008726945
AG-99 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DQA1 Gene (Entity type)	-0.010224852

ST-4039884
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.009530269

3-Methyl-1-propyl-3,7-dihydro-purine-2,6-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
0.0025525296

norcitalopram
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
0.015523461

Pentolinium
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.023505596

rhodomyrtoxin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.015554273

4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.0062881475

Pemoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.009755737

2-Methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene (Olanzapine)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.0055798762

SA-1463785
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
0.008726945

AG-99
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HLA-DQA1
Gene (Entity type)
-0.010224852

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.