MX2 (Gene)

Entrez Gene ID: 4600

Description: MX dynamin like GTPase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MX2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MX2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MX2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MX2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MX2.

Gene Sets (3965)

LINCS L1000 Chem Pert Consensus Sigs (756)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (10)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1230)

A gene set library provided by LINCS

rummageo gene perturbations (177)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (306)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1218)

A gene set library provided by LINCS

rummageo chemical perturbations (259)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ML-7 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.008316961
Etoposide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	0.0057441923
TL-HRAS-27 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.010014979
Skatole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	0.009233142
oxindole-I Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.009559582
Terguride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.01056375
1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one (Azaperone) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.0068271263
meclocycline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	0.010634569
Sulforaphane Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	-0.0043928735
2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MX2 Gene (Entity type)	0.0105728945

ML-7
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.008316961

Etoposide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
0.0057441923

TL-HRAS-27
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.010014979

Skatole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
0.009233142

oxindole-I
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.009559582

Terguride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.01056375

1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one (Azaperone)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.0068271263

meclocycline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
0.010634569

Sulforaphane
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
-0.0043928735

2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MX2
Gene (Entity type)
0.0105728945

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.