EHMT1 (Gene)

Organism:

Homo sapiens

Synonyms:EHMT1, EHMT1-IT1, ENTREZ:79813, EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, HGNC:24650, KLEFS1, KMT1D, MIM:607001, NM_001039765, NM_001145527, NM_001354259, NM_001354263, NM_001354611, NM_001354612, NM_024757, NP_001138999, NP_001341188, NP_001341192, NP_001341540, NP_001341541, NP_079033, XM_005266105, XM_005266110, XM_011519021, XM_011519022, XM_011519023, XM_011519025, XM_011519029, XM_011519030, XM_011519031, XM_017015134, XM_017015136, XM_017015137, XM_017015138, XM_024447674, XM_024447675, XM_024447676, XM_024447677, XM_024447678, XM_024447679, XM_024447680, XP_005266162, XP_005266167, XP_011517323, XP_011517324, XP_011517325, XP_011517327, XP_011517331, XP_011517332, XP_011517333, XP_016870623, XP_016870625, XP_016870626, XP_016870627, XP_024303442, XP_024303443, XP_024303444, XP_024303445, XP_024303446, XP_024303447, XP_024303448, euchromatic histone lysine methyltransferase 1

Omim:OMIM:607001

Id:ENSG00000181090

Hgnc:HGNC:24650

Entrez:79813

Ensembl:ENSG00000181090

Description:euchromatic histone lysine methyltransferase 1

The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EHMT1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EHMT1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EHMT1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EHMT1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EHMT1.

Results found

Linked to

	Label	Description
	GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193993 SSTR2 knockout 4 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 trametinib NF1 8 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233647 docetaxel UFERSA-PC3 DU145 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE197422 GSE197424 FN1 overexpression HGC-27 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE153867 olaparib 6 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE252944 AKT inhibition 7 v 14 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE235390 4 V 0 LURBINECTEDIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 saha 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE179667 NVP-BEZ235 U-87MG Uppsala 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193993 SSTR2 knockout 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 trametinib NF1 8 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233647 docetaxel UFERSA-PC3 DU145 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE197422 GSE197424 FN1 overexpression HGC-27 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE153867 olaparib 6 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE252944 AKT inhibition 7 v 14 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE235390 4 V 0 LURBINECTEDIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE77108 saha 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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