CDH5 (Gene)

Organism:

Homo sapiens

Synonyms:7B4, CD144, CDH5, ENTREZ:1003, HGNC:1764, MIM:601120, NM_001114117, NM_001795, NP_001786, XM_011522801, XM_024450133, XP_011521103, XP_024305901, cadherin 5

Omim:OMIM:601120

Id:ENSG00000179776

Hgnc:HGNC:1764

Entrez:1003

Ensembl:ENSG00000179776

Description:cadherin 5

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CDH5's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CDH5.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CDH5.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CDH5.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CDH5.

Results found

Linked to

	Label	Description
	T60-Adrenal Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE261563 CX-5461 7 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 saha 4 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE261563 CX-5461 5 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE176008 pyridoxine 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE133749 BMPR2 overexpression endothelial cell 0 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 10 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226115 GSE226116 doxorubicin cardiac endothelial cell 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 15 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE207122 metformin 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE261563 CX-5461 7 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE77108 saha 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE261563 CX-5461 5 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE176008 pyridoxine 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE133749 BMPR2 overexpression endothelial cell 0 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 10 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226115 GSE226116 doxorubicin cardiac endothelial cell 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 15 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE207122 metformin 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.