NKX3-1 (Gene)

Entrez Gene ID: 4824

Description: NK3 homeobox 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NKX3-1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NKX3-1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NKX3-1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NKX3-1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NKX3-1.

Gene Sets (1537)

LINCS L1000 Chem Pert Consensus Sigs (866)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (663)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (6)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
BW-723C86 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	-0.0077121914
Tilmicosin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	-0.03764523
BIX-02188 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	-0.0070878277
hydrastine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	-0.00784912
norgestimate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	0.008967489
RITA Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	0.0052014175
N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	0.004379892
SA-247508 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	-0.012612633
SR57227A Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	0.0036286856
ARG-CSC-22 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX3-1 Gene (Entity type)	0.007812045

BW-723C86
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
-0.0077121914

Tilmicosin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
-0.03764523

BIX-02188
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
-0.0070878277

hydrastine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
-0.00784912

norgestimate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
0.008967489

RITA
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
0.0052014175

N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
0.004379892

SA-247508
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
-0.012612633

SR57227A
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
0.0036286856

ARG-CSC-22
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NKX3-1
Gene (Entity type)
0.007812045

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Knowledge Graph Assertions

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.