TMEM100 (Gene)

Entrez Gene ID: 55273

Description: transmembrane protein 100

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TMEM100's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TMEM100.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TMEM100.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TMEM100.

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Gene Sets (2757)

LINCS L1000 Chem Pert Consensus Sigs (713)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (9)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (697)

A gene set library provided by LINCS

rummageo gene perturbations (105)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (1096)

A gene set library provided by LINCS

rummageo chemical perturbations (121)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (12)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
AZD-1152 HQPA Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.0029562018
Clindamycin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	-0.0041599264
2-hydroxy-5-(2-[{hydroxy-3-(4-[1-methyl-4-trifluoromethyl-2-imidazolyl]phenoxy)propyl}amino]-ethoxy)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.008905874
tebuthiuron Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	-0.0077259094
Carmoxirole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.0097618075
SID11113608 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.008063602
N-(2,6-dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	-0.008206382
prostaglandin-b2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.008770411
deoxycorticosterone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	0.0045571667
(E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM100 Gene (Entity type)	-0.0032462215

AZD-1152 HQPA
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.0029562018

Clindamycin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
-0.0041599264

2-hydroxy-5-(2-[{hydroxy-3-(4-[1-methyl-4-trifluoromethyl-2-imidazolyl]phenoxy)propyl}amino]-ethoxy)benzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.008905874

tebuthiuron
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
-0.0077259094

Carmoxirole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.0097618075

SID11113608
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.008063602

N-(2,6-dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
-0.008206382

prostaglandin-b2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.008770411

deoxycorticosterone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
0.0045571667

(E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM100
Gene (Entity type)
-0.0032462215

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.