NOLC1 (Gene)

Entrez Gene ID: 9221

Description: nucleolar and coiled-body phosphoprotein 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NOLC1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NOLC1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NOLC1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NOLC1.

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Gene Sets (1650)

LINCS L1000 Chem Pert Consensus Sigs (411)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (340)

A gene set library provided by LINCS

rummageo gene perturbations (278)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (180)

A gene set library provided by LINCS

rummageo chemical perturbations (435)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
curcumin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	0.0029012898
Anagrelide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	0.0028888877
SID103905167 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	0.007079265
7b-cis Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.013772576
KFGENEBIN:NOLC1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)
dichlorobenzamil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.009642179
3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.009550092
Hydroxyamphetamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.03607906
4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.0078105642
[3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-propyl]-methyl-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOLC1 Gene (Entity type)	-0.0032220252

curcumin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
0.0029012898

Anagrelide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
0.0028888877

SID103905167
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
0.007079265

7b-cis
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.013772576

KFGENEBIN:NOLC1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)

dichlorobenzamil
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.009642179

3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.009550092

Hydroxyamphetamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.03607906

4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.0078105642

[3-(5H-Dibenzo[a,d]cyclohepten-5-yl)-propyl]-methyl-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NOLC1
Gene (Entity type)
-0.0032220252

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.