ERAP1 (Gene)

Entrez Gene ID: 51752

Description: endoplasmic reticulum aminopeptidase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ERAP1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ERAP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ERAP1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ERAP1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ERAP1.

Gene Sets (1914)

LINCS L1000 Chem Pert Consensus Sigs (301)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (2)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (199)

A gene set library provided by LINCS

rummageo gene perturbations (188)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (460)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (409)

A gene set library provided by LINCS

rummageo chemical perturbations (342)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (1)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
doxorubicin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	0.0075114304
Psoromic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	-0.013242995
KU-C104228 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	-0.010511491
Tegaserod Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	-0.012896848
2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	0.008451888
Edaravone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	-0.0037531261
KFGENEBIN:ERAP1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)
diphemanil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ERAP1 Gene (Entity type)	0.0090446975

doxorubicin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
0.0075114304

Psoromic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
-0.013242995

KU-C104228
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
-0.010511491

Tegaserod
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
-0.012896848

2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
0.008451888

Edaravone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
-0.0037531261

KFGENEBIN:ERAP1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)

diphemanil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ERAP1
Gene (Entity type)
0.0090446975

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.