IFI16 (Gene)

Entrez Gene ID: 3428

Description: interferon gamma inducible protein 16

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IFI16's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IFI16.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IFI16.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IFI16.

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Gene Sets (3895)

LINCS L1000 Chem Pert Consensus Sigs (897)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1067)

A gene set library provided by LINCS

rummageo gene perturbations (252)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1249)

A gene set library provided by LINCS

rummageo chemical perturbations (422)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Tolperisone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	0.004364969
Thiamylal Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	0.005461409
4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	0.0047356556
salsolinol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	-0.007997946
KFGENEBIN:IFI16-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)
Cefepime Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	-0.005505766
SD-6-035-B4 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	0.008074206
3-[1-(1-Methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	-0.008347579
4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	-0.010237065
BG-1029 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI16 Gene (Entity type)	-0.017574908

Tolperisone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
0.004364969

Thiamylal
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
0.005461409

4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
0.0047356556

salsolinol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
-0.007997946

KFGENEBIN:IFI16-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)

Cefepime
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
-0.005505766

SD-6-035-B4
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
0.008074206

3-[1-(1-Methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
-0.008347579

4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
-0.010237065

BG-1029
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI16
Gene (Entity type)
-0.017574908

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.