GNE (Gene)

Entrez Gene ID: 10020

Description: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GNE's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GNE.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GNE.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GNE.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GNE.

Gene Sets (1701)

LINCS L1000 Chem Pert Consensus Sigs (312)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (4)

A gene set library provided by MW

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (10)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (166)

A gene set library provided by LINCS

rummageo gene perturbations (174)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (348)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (448)

A gene set library provided by LINCS

rummageo chemical perturbations (237)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
YS-035 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	0.003950622
GNE Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Uridine Diphosphate Metabolite (Entity type)
GNE Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ADP Metabolite (Entity type)
methyllidocaine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	-0.008244266
ST-019366 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	-0.0093937935
Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4-yl)-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	-0.00932777
BG-1016 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	-0.017981658
isorotenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNE Gene (Entity type)	-0.007951438
GNE Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
GNE Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Adenosine Diphosphate Metabolite (Entity type)

YS-035
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
0.003950622

GNE
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Uridine Diphosphate
Metabolite (Entity type)

GNE
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ADP
Metabolite (Entity type)

methyllidocaine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
-0.008244266

ST-019366
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
-0.0093937935

Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4-yl)-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
-0.00932777

BG-1016
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
-0.017981658

isorotenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNE
Gene (Entity type)
-0.007951438

GNE
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

GNE
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Adenosine Diphosphate
Metabolite (Entity type)

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.