XDH (Gene)

Entrez Gene ID: 7498

Description: xanthine dehydrogenase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View XDH's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with XDH.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using XDH.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for XDH.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with XDH.

Gene Sets (542)

LINCS L1000 Chem Pert Consensus Sigs (2)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (2)

A gene set library provided by MW

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (5)

A gene set library provided by LINCS

rummageo gene perturbations (87)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (14)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (268)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (5)

A gene set library provided by LINCS

rummageo chemical perturbations (138)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

IDG Drug Targets 2022 (5)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	theobromine Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	7-methylxanthine Metabolite (Entity type)
KFGENEBIN:XDH-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	XDH Gene (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	3,7-dimethyluric acid Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nadide Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	7-Methyluric acid Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	xanthine Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	uric acid Metabolite (Entity type)
XDH Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	1-methylxanthine Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
theobromine
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
7-methylxanthine
Metabolite (Entity type)

KFGENEBIN:XDH-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
XDH
Gene (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
3,7-dimethyluric acid
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
nicotinamide adenine dinucleotide (NAD)
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
nadide
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
7-Methyluric acid
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
xanthine
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
uric acid
Metabolite (Entity type)

XDH
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
1-methylxanthine
Metabolite (Entity type)

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.