CACNA2D3 (Gene)

Synonyms:CACNA2D3, ENTREZ:55799, HGNC:15460, HSA272268, MIM:606399, NM_018398, NP_060868, calcium voltage-gated channel auxiliary subunit alpha2delta 3
Omim:OMIM:606399
Id:ENSG00000157445
Hgnc:HGNC:15460
Entrez:55799
Description:calcium voltage-gated channel auxiliary subunit alpha2delta 3
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

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