CACNA1D (Gene)

Organism:

Homo sapiens

Synonyms:CACH3, CACN4, CACNA1D, CACNL1A2, CCHL1A2, Cav1.3, ENTREZ:776, HGNC:1391, MIM:114206, NM_000720, NM_001128839, NM_001128840, NP_000711, NP_001122311, NP_001122312, PASNA, SANDD, XM_005265448, XM_011534094, XM_011534096, XM_011534097, XM_011534099, XM_011534100, XM_017007137, XM_017007138, XM_017007139, XM_017007140, XM_017007141, XM_017007142, XM_017007143, XM_017007144, XM_017007145, XP_005265505, XP_011532396, XP_011532398, XP_011532399, XP_011532401, XP_011532402, XP_016862626, XP_016862627, XP_016862628, XP_016862629, XP_016862630, XP_016862631, XP_016862632, XP_016862633, XP_016862634, calcium voltage-gated channel subunit alpha1 D

Omim:OMIM:114206

Nci:C113769

Id:ENSG00000157388

Hgnc:HGNC:1391

Entrez:776

Ensembl:ENSG00000157388

Description:calcium voltage-gated channel subunit alpha1 D

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CACNA1D's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CACNA1D.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CACNA1D.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CACNA1D.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CACNA1D.

Results found

Linked to

	Label	Description
	GSE197422 GSE197424 FN1 overexpression HGC-27 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135514 dasatinib 8 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 8 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE147876 GSE147877 enzalutamide MR42D 2 v 10 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE143948 ZNF213 knockdown MCF-7 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 6 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE183041 cisplatin 1 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE226525 GSE226527 HNRNPH2 knockout 4 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE147876 GSE147877 enzalutamide MR42D 2 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE197422 GSE197424 FN1 overexpression HGC-27 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE135514 dasatinib 8 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 8 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE147876 GSE147877 enzalutamide MR42D 2 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE143948 ZNF213 knockdown MCF-7 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 6 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE183041 cisplatin 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE226525 GSE226527 HNRNPH2 knockout 4 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE147876 GSE147877 enzalutamide MR42D 2 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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